Across TCGA pan-cancer cohorts, LINC00424 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LINC00424 data layer.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC00424 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC00424 expression acts as an unfavorable survival marker, although some lineages such as HNSC and MESO show a favorable association.
HNSC, MESO, and LIHC are the cancer types where LINC00424 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.