LINC00407

Across TCGA pan-cancer cohorts, LINC00407 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC00407’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC00407 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00407 is over-expressed in tumor, although a few such as LUSC and UCEC show the opposite, repressed pattern.

LUSC, UCEC, and KIRC are the cancer types where LINC00407 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00407 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	−0.188	<.001	8	view →
UCEC	All	IV	−0.940	.001	6	view →
KIRC	Male	II,III,IV	−0.111	<.001	5	view →
READ	All	II,III,IV	−0.192	.029	3	view →
KIRP	Female	All	−0.193	.021	2	view →
KICH	All	All	−0.133	.046	1	view →
HNSC	All	IV	−0.051	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC00407–LUSC

Open the LUSC breakdown →