LINC00402

Across TCGA pan-cancer cohorts, LINC00402 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC00402 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC00402 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00402 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and LIHC are the cancer types where LINC00402 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.739	0.590	<.001	152	view →
SKCM	OS	Median	All	0.836	0.726	<.001	96	view →
LIHC	OS	Tertile	II,III,IV	0.723	0.275	<.001	74	view →
LUAD	DFS	Median	All	0.846	0.734	<.001	67	view →
CESC	DFS	Tertile	All	0.834	0.623	<.001	66	view →
ESCA	DFS	Median	All	0.440	0.235	.001	65	view →
UVM	DFS	Tertile	All	0.293	0.617	.010	51	view →
UCS	DFS	Tertile	II,III,IV	0.634	0.250	.008	30	view →
BRCA	OS	Median	All	0.604	0.543	.019	20	view →
STAD	DFS	Median	All	0.453	0.608	.025	20	view →
KIRP	DFS	Median	All	0.532	0.907	.004	18	view →
PRAD	DFS	Tertile	All	0.884	0.763	.005	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC00402–HNSC (DFS)

Open the HNSC breakdown →