LINC00393

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00393 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LINC00393 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC00393 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00393 expression acts as an unfavorable survival marker, although some lineages such as LUSC and CESC show a favorable association.

UVM, LUSC, and LGG are the cancer types where LINC00393 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSQuartileAll0.5540.980.00178view →
LUSCOSMedianAll0.8100.707.00165view →
LGGDFSQuartileAll0.6190.776<.00137view →
CESCDFSMedianII,III,IV0.8870.680<.00128view →
CHOLOSTertileIII,IV0.2750.886.04518view →
KIRPOSTertileIV0.1110.503<.00118view →
BRCADFSMedianIV0.3360.671.00715view →
BLCADFSMedianIV0.3310.118.00212view →
COADOSMedianIV0.7660.262.00912view →
KICHOSTertileIII,IV1.0000.671.0317view →
KIRCDFSTertileIV0.7400.575.0336view →
ESCADFSTertileAll0.4520.637.0256view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration