LINC00384

Across TCGA pan-cancer cohorts, LINC00384 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC00384 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC00384 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00384 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, ACC, and KIRC are the cancer types where LINC00384 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.445	0.282	<.001	106	view →
ACC	OS	Median	II,III,IV	0.728	0.931	.001	56	view →
KIRC	DFS	Tertile	IV	0.161	0.466	.003	44	view →
UVM	DFS	Quartile	All	0.282	0.801	<.001	39	view →
LUAD	DFS	Tertile	II,III,IV	0.736	0.408	<.001	38	view →
KIRP	DFS	Tertile	II,III,IV	0.040	0.825	.002	29	view →
BLCA	OS	Median	All	0.498	0.281	.009	28	view →
LUSC	OS	Tertile	III,IV	0.275	0.610	.011	28	view →
SKCM	OS	Median	III,IV	0.791	0.608	.005	28	view →
CESC	DFS	Tertile	All	0.837	0.677	.001	28	view →
TGCT	DFS	Quartile	II,III,IV	0.560	1.000	.017	26	view →
THCA	DFS	Median	II,III,IV	0.838	0.646	.005	26	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC00384–HNSC (DFS)

Open the HNSC breakdown →