LINC00380

Across TCGA pan-cancer cohorts, LINC00380 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LINC00380 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LINC00380 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00380 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

BLCA, THCA, and UCS are the cancer types where LINC00380 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	III,IV	0.137	0.687	<.001	72	view →
THCA	DFS	Tertile	All	0.573	0.896	<.001	54	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
UCEC	OS	Tertile	All	0.747	0.881	.001	36	view →
GBM	OS	Tertile	All	0.024	0.416	<.001	18	view →
PAAD	DFS	Tertile	II,III,IV	0.203	0.440	.020	18	view →
CESC	DFS	Tertile	II,III,IV	0.146	0.705	.010	18	view →
DLBC	DFS	Tertile	III,IV	0.137	0.790	<.001	18	view →
KIRC	DFS	Quartile	All	0.861	0.779	.006	15	view →
OV	OS	Tertile	IV	1.000	0.705	.023	12	view →
SKCM	OS	Tertile	III,IV	0.232	0.702	.005	12	view →
KIRP	DFS	Tertile	All	1.000	0.826	.026	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LINC00380–BLCA (OS)

Open the BLCA breakdown →