LINC00373

Across TCGA pan-cancer cohorts, LINC00373 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated LINC00373 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC00373 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00373 expression acts as an unfavorable survival marker, although some lineages such as CHOL and STAD show a favorable association.

HNSC, ACC, and UCEC are the cancer types where LINC00373 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.203	0.613	<.001	45	view →
ACC	OS	Tertile	All	0.188	0.820	<.001	36	view →
UCEC	DFS	Tertile	All	0.658	0.843	.027	24	view →
COAD	DFS	Tertile	III,IV	0.005	0.650	<.001	18	view →
CHOL	DFS	Tertile	All	1.000	0.329	.020	18	view →
LUAD	OS	Tertile	II,III,IV	0.256	0.552	.026	18	view →
STAD	DFS	Tertile	III,IV	0.642	0.439	.033	15	view →
LIHC	DFS	Tertile	II,III,IV	0.121	0.419	.026	15	view →
LUSC	OS	Tertile	All	0.555	0.749	.027	9	view →
BLCA	OS	Tertile	III,IV	0.650	0.341	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

LINC00373–HNSC (OS)

Open the HNSC breakdown →