LINC00366

Across TCGA pan-cancer cohorts, LINC00366 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC00366’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00366 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00366 is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and THCA are the cancer types where LINC00366 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00366 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	−0.022	.011	4	view →
LUAD	All	II,III,IV	−0.077	.016	1	view →
THCA	All	All	−0.023	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC00366–KIRC

Open the KIRC breakdown →