LINC00345

Across TCGA pan-cancer cohorts, LINC00345 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC00345’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC00345 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00345 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

LIHC, BRCA, and KICH are the cancer types where LINC00345 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00345 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.094	.003	3	view →
BRCA	Female	All	−0.077	.039	2	view →
KICH	All	All	−0.265	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC00345–LIHC

Open the LIHC breakdown →