Across TCGA pan-cancer cohorts, LINC00343 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00343’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00343 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00343 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.
KIRC, KICH, and UCEC are the cancer types where LINC00343 tumor–normal differential expression is most reproducible.