LINC00336

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00336 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LINC00336 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LINC00336 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00336 expression acts as an unfavorable survival marker.

LUAD, BRCA, and PAAD are the cancer types where LINC00336 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianAll0.0530.835<.00148view →
BRCAOSMedianAll0.2870.924<.00136view →
PAADOSMedianII,III,IV0.1460.557<.00124view →
BLCADFSMedianAll0.1790.625.0296view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration