LINC00330

Across TCGA pan-cancer cohorts, LINC00330 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00330’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00330 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00330 is over-expressed in tumor, although a few such as HNSC and KIRC show the opposite, repressed pattern.

HNSC, KIRC, and KIRP are the cancer types where LINC00330 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00330 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	−1.687	<.001	12	view →
KIRC	Male	II,III,IV	−0.147	<.001	11	view →
KIRP	All	All	−0.132	<.001	10	view →
LUAD	All	All	+0.141	.002	7	view →
THCA	Male	All	−0.097	<.001	7	view →
STAD	All	II,III,IV	−0.510	.027	3	view →
UCEC	All	All	+0.246	.042	2	view →
KICH	All	III,IV	−0.108	.009	2	view →
BRCA	All	III,IV	−0.014	.023	2	view →
COAD	Female	IV	+0.240	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC00330–HNSC

Open the HNSC breakdown →