LINC00301

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00301 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00301-associated genes across cancer lineages are MIR4296, COX6CP3, and SMIM11P1. Each is linked with LINC00301 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00301-to-partner and partner-to-LINC00301 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4296 grouped by LINC00301-low versus LINC00301-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00301→partner) and Y-score (partner→LINC00301) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR4296 →+0.978+4.130.001.00431
UCECCOX6CP3 →+0.342+4.262<.001.00331
UCECSMIM11P1 →+0.403+3.969.003.00531
UCECRNA5SP405 →+0.942+4.997<.001.00331
UCECRNA5SP199 →+1.417+4.262<.001.00331
UCECRNA5SP50 →+1.829+4.352<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

MIR4296 by LINC00301 expression — UCEC

Box plot of MIR4296 in LINC00301-low vs LINC00301-high samples in UCEC.

Explore this box plot interactively →

Exploration