LINC00294

Across TCGA pan-cancer cohorts, LINC00294 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC00294 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher LINC00294 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00294 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

LIHC, MESO, and KIRC are the cancer types where LINC00294 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.471	0.613	<.001	78	view →
MESO	DFS	Median	III,IV	0.267	0.471	.001	54	view →
KIRC	DFS	Tertile	All	0.872	0.696	.001	52	view →
BLCA	DFS	Tertile	All	0.481	0.746	.004	42	view →
HNSC	OS	Tertile	IV	0.499	0.858	.001	41	view →
PAAD	OS	Median	All	0.696	0.473	.002	35	view →
LGG	OS	Median	All	0.499	0.383	<.001	29	view →
ACC	DFS	Quartile	All	0.225	0.763	<.001	24	view →
KIRP	DFS	Quartile	All	0.620	0.773	.013	19	view →
STAD	DFS	Tertile	IV	0.174	0.670	.017	15	view →
SKCM	DFS	Tertile	III,IV	0.512	0.811	.005	13	view →
THYM	DFS	Median	II,III,IV	0.946	0.512	.005	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC00294–LIHC (DFS)

Open the LIHC breakdown →