LINC00278

Across TCGA pan-cancer cohorts, LINC00278 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LINC00278 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC00278 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00278 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UVM show a favorable association.

HNSC, UVM, and ESCA are the cancer types where LINC00278 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.395	0.257	.001	99	view →
UVM	DFS	Median	All	0.916	0.572	.008	39	view →
ESCA	OS	Tertile	All	0.307	0.894	.012	27	view →
LUAD	OS	Median	All	0.735	0.832	.010	23	view →
SKCM	DFS	Tertile	III,IV	0.064	0.656	<.001	18	view →
COAD	DFS	Tertile	III,IV	0.248	0.629	.017	18	view →
MESO	DFS	Quartile	All	0.389	0.217	.008	16	view →
LGG	DFS	Quartile	All	0.337	0.616	<.001	16	view →
KIRP	DFS	Median	All	0.480	0.691	.017	15	view →
BLCA	OS	Median	III,IV	0.429	0.305	.014	14	view →
PRAD	DFS	Tertile	All	0.861	0.683	.010	12	view →
ACC	DFS	Median	All	0.870	0.585	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LINC00278–HNSC (DFS)

Open the HNSC breakdown →