LINC00273

Across TCGA pan-cancer cohorts, LINC00273 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated LINC00273 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher LINC00273 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00273 expression acts as an unfavorable survival marker, although some lineages such as BRCA and STAD show a favorable association.

PAAD, UCS, and BRCA are the cancer types where LINC00273 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.300	0.619	.004	54	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
BRCA	OS	Tertile	All	0.984	0.919	.025	12	view →
LGG	DFS	Tertile	All	0.364	0.737	.018	12	view →
STAD	OS	Median	IV	0.556	0.220	.007	10	view →
MESO	OS	Tertile	IV	0.134	0.629	.002	9	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →
ESCA	OS	Tertile	IV	0.743	0.243	.024	6	view →
COAD	OS	Tertile	All	0.619	0.812	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

LINC00273–PAAD (OS)

Open the PAAD breakdown →