Across TCGA pan-cancer cohorts, LINC00272 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00272’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00272 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00272 is over-expressed in tumor, although a few such as THCA and READ show the opposite, repressed pattern.
KIRC, LIHC, and THCA are the cancer types where LINC00272 tumor–normal differential expression is most reproducible.