Across TCGA pan-cancer cohorts, LINC00269 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00269’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00269 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00269 is over-expressed in tumor, although a few such as PRAD show the opposite, repressed pattern.

KIRC, BLCA, and KIRP are the cancer types where LINC00269 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00269 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.022	<.001	6	view →
BLCA	All	All	+0.021	.029	3	view →
KIRP	Male	All	+0.040	.033	2	view →
PRAD	All	All	−0.010	.008	2	view →
LUAD	All	All	+0.018	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: LINC00269 RNA expression & survival · all LINC00269 data types