LINC00265-3P

Across TCGA patient cohorts, LINC00265-3P RNA expression is significantly associated with the go_rna of many other GO terms, with 270 significant associations in total. THCA shows the largest number of these associations.

The most reproducible LINC00265-3P-associated GO terms across cancer lineages are Positive regulation of receptor signaling pathway via STAT, Regulation of membrane protein ectodomain proteolysis, and Cellular response to ethanol. Each is linked with LINC00265-3P in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00265-3P-to-partner and partner-to-LINC00265-3P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of receptor signaling pathway via STAT grouped by LINC00265-3P-low versus LINC00265-3P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00265-3P→partner) and Y-score (partner→LINC00265-3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of receptor signaling pathway via STAT →	+0.042	+0.018	<.001	<.001	3	1
ESCA	Regulation of membrane protein ectodomain proteolysis →	+0.041	+0.014	.008	<.001	3	1
ESCA	Cellular response to ethanol →	+0.045	+0.016	.001	.004	3	1
OV	Sulfate transport →	+0.044	+0.004	.002	<.001	3	1
LAML	Maintenance of lens transparency →	+0.110	+0.015	.001	.004	3	1
THCA	Positive regulation of cell cycle phase transition →	+0.023	+0.004	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

Positive regulation of receptor signaling pathway via STAT by LINC00265-3P expression — ESCA

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