LINC00254

Across TCGA pan-cancer cohorts, LINC00254 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LINC00254 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher LINC00254 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00254 expression acts as an unfavorable survival marker.

PAAD, LIHC, and READ are the cancer types where LINC00254 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	II,III,IV	0.211	0.562	<.001	63	view →
LIHC	OS	Tertile	All	0.028	0.775	<.001	63	view →
READ	OS	Tertile	All	0.222	0.845	<.001	54	view →
LUSC	OS	Tertile	II,III,IV	0.197	0.635	.002	45	view →
KIRP	OS	Tertile	All	0.203	0.700	<.001	36	view →
HNSC	OS	Tertile	IV	0.001	0.643	<.001	36	view →
THCA	OS	Tertile	All	0.240	0.931	<.001	27	view →
KIRC	DFS	Tertile	All	0.435	0.654	.017	24	view →
BRCA	DFS	Tertile	All	0.787	0.906	.001	24	view →
BLCA	DFS	Tertile	All	0.258	0.528	.032	18	view →
SKCM	DFS	Tertile	III,IV	0.043	0.597	<.001	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

LINC00254–PAAD (OS)

Open the PAAD breakdown →