Across TCGA pan-cancer cohorts, LINC00229 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC00229’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC00229 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00229 is over-expressed in tumor.
LIHC are the cancer types where LINC00229 tumor–normal differential expression is most reproducible.