long intergenic non-protein coding RNA 205Genealiases: LVBU · NCRNA00205
Q-omics provides the consensus-scored LINC00205 profile across patient tissues and cancer cell-line models. LINC00205 expression is associated with patient survival in 30 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, LINC00205 is differentially expressed in 15, with the highest sampling consensus in HNSC. Additionally, LINC00205 RNA expression shows 19,288 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and HNSC as cancer lineages where LINC00205 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00205 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00205 survival associations across molecular data types. LINC00205 RNA expression shows survival associations in the most cancer types (30), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00205 RNA expression–survival associations across cancer types. High LINC00205 expression shows unfavorable associations in ACC, LIHC, MESO, LUAD and STAD, but favorable associations in UCS. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for LINC00205 RNA expression.
This table summarizes LINC00205 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00205. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00205 shows lower tumor expression in THCA and KICH and higher tumor expression in HNSC, LIHC, LUAD and KIRP. The HNSC box plot shows higher LINC00205 RNA expression in tumor versus normal tissue (log2 FC = +1.005, t-test p < 0.001).
This table shows molecular features associated with LINC00205 in patient tissues and cancer cell lines. In patient samples, LINC00205 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, LINC00205 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in KIDNEY, while CRISPR and shRNA rows add functional-dependency signals in OVARY.
