LINC00163

Across TCGA pan-cancer cohorts, LINC00163 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC00163 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher LINC00163 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00163 expression acts as an unfavorable survival marker, although some lineages such as CHOL and READ show a favorable association.

BRCA, COAD, and ACC are the cancer types where LINC00163 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Quartile	III,IV	0.807	0.916	.001	67	view →
COAD	OS	Quartile	III,IV	0.160	0.759	<.001	59	view →
ACC	OS	Tertile	All	0.311	0.791	<.001	57	view →
LIHC	OS	Quartile	II,III,IV	0.372	0.655	<.001	49	view →
UCEC	DFS	Tertile	All	0.507	0.715	<.001	42	view →
KIRP	DFS	Tertile	III,IV	0.161	0.694	.004	34	view →
KIRC	DFS	Quartile	IV	0.358	0.668	.001	31	view →
CHOL	OS	Tertile	All	0.918	0.451	.006	30	view →
KICH	OS	Quartile	II,III,IV	0.587	0.971	.002	24	view →
CESC	OS	Median	All	0.716	0.867	<.001	24	view →
LUSC	DFS	Median	III,IV	0.405	0.884	.006	20	view →
MESO	OS	Tertile	All	0.210	0.412	.014	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC00163–BRCA (DFS)

Open the BRCA breakdown →