LINC00159

Across TCGA pan-cancer cohorts, LINC00159 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC00159’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LINC00159 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00159 is over-expressed in tumor, although a few such as COAD and STAD show the opposite, repressed pattern.

COAD, THCA, and UCEC are the cancer types where LINC00159 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00159 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	−0.089	<.001	4	view →
THCA	All	IV	+0.255	.029	2	view →
UCEC	All	All	+0.231	.047	2	view →
KIRC	All	III,IV	+0.039	.034	2	view →
STAD	All	All	−0.114	.024	1	view →
THCA	Female	All	−0.077	.025	1	view →
CHOL	All	All	+0.063	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 6 lineages.

LINC00159–COAD

Open the COAD breakdown →