Across TCGA pan-cancer cohorts, LINC00158 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC00158’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00158 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00158 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
KIRC, HNSC, and LUAD are the cancer types where LINC00158 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00158 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.