Across TCGA pan-cancer cohorts, LIN9 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LIN9 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LIN9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LIN9 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BLCA, UCEC, and PCPG are the cancer types where LIN9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.157	0.618	.004	24	view →
UCEC	DFS	Median	II,III,IV	0.937	0.431	.010	22	view →
PCPG	OS	Median	All	0.010	0.946	<.001	12	view →
LUAD	DFS	Median	All	0.206	0.767	.006	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: LIN9 tumor-vs-normal RNA expression · all LIN9 data types