Across TCGA patient cohorts, LIN9 protein abundance is significantly associated with the RNA expression of many other genes, with 12,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIN9-associated genes across cancer lineages are RAD54L, NOP56, and NSD2. Each is linked with LIN9 in more than 5 cancer types. Because this analysis shows association rather than direction, both LIN9-to-partner and partner-to-LIN9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN9→partner) and Y-score (partner→LIN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAD54L →	+0.770	+0.312	<.001	<.001	3	6
LSCC	NOP56 →	+0.570	+0.223	<.001	<.001	3	5
LSCC	NSD2 →	+0.642	+0.223	.001	.004	3	5
LSCC	PIMREG →	+1.107	+0.261	<.001	<.001	3	5
BRCA	CDCA5 →	+1.099	+0.297	<.001	<.001	3	5
LSCC	RAD54B →	+0.505	+0.207	.002	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,032 associations by consensus.

Exploration

LIN9 survival (RNA) · tumor vs normal (RNA) · all LIN9 data types