LIN7C

Across TCGA cell cohorts, LIN7C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,003 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LIN7C-associated GO terms across cancer lineages are Vesicle coating, Positive regulation of cytoplasmic translation, and Nucleotide-excision repair. Each is linked with LIN7C in more than 10 cancer types. Because this analysis shows association rather than direction, both LIN7C-to-partner and partner-to-LIN7C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle coating grouped by LIN7C-low versus LIN7C-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN7C→partner) and Y-score (partner→LIN7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Vesicle coating →	+0.069	+0.520	<.001	.001	3	11
SKIN	Positive regulation of cytoplasmic translation →	+0.071	+0.504	.002	.005	3	9
BLOOD_Myeloma	Nucleotide-excision repair →	+0.036	+0.837	.004	.004	3	8
SKIN	snRNA metabolic process →	+0.035	+0.432	.001	<.001	3	8
OVARY	Monoubiquitinated protein deubiquitination →	+0.101	+0.601	.006	.002	2	9
KIDNEY	Regulation of centriole replication →	+0.070	+0.658	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,003 associations by consensus.

Vesicle coating by LIN7C expression — SKIN

Explore this box plot interactively →