LIN7B

Across TCGA patient cohorts, LIN7B protein abundance is significantly associated with the RNA expression of many other genes, with 6,867 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIN7B-associated genes across cancer lineages are GAL3ST1, LGALS3, and GLT1D1. Each is linked with LIN7B in more than 1 cancer types. Because this analysis shows association rather than direction, both LIN7B-to-partner and partner-to-LIN7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIN7B versus GAL3ST1 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN7B→partner) and Y-score (partner→LIN7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GAL3ST1 →	+0.919	+0.521	<.001	<.001	3	2
GBM	LGALS3 →	-0.943	-0.359	.008	.002	3	2
GBM	GLT1D1 →	+0.816	+0.446	<.001	<.001	3	2
LUAD	SHOC1 →	-1.369	-0.686	.009	.004	3	2
HNSC	GLIPR1 →	-0.862	-0.534	.002	<.001	3	2
HNSC	RN7SL477P →	+1.083	+0.619	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,867 associations by consensus.

LIN7B vs GAL3ST1 — GBM

Explore this scatter interactively →