LIN7B

Across TCGA cell cohorts, LIN7B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,454 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LIN7B-associated GO terms across cancer lineages are Establishment of vesicle localization, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Vesicle localization. Each is linked with LIN7B in more than 13 cancer types. Because this analysis shows association rather than direction, both LIN7B-to-partner and partner-to-LIN7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of vesicle localization grouped by LIN7B-low versus LIN7B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN7B→partner) and Y-score (partner→LIN7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Establishment of vesicle localization →	+0.064	+1.438	.003	.002	3	14
KIDNEY	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.128	+0.785	<.001	<.001	3	13
BREAST	Vesicle localization →	+0.055	+1.326	<.001	<.001	3	12
KIDNEY	Negative regulation of calcium ion export across plasma membrane →	+0.068	+0.817	<.001	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal protein catabolic process →	+0.050	+0.766	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.052	+0.782	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,454 associations by consensus.

Establishment of vesicle localization by LIN7B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →