LIN7A

Across TCGA cell cohorts, LIN7A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,825 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LIN7A-associated GO terms across cancer lineages are CMP catabolic process, Regulation of cell adhesion mediated by integrin, and ERBB2-EGFR signaling pathway. Each is linked with LIN7A in more than 7 cancer types. Because this analysis shows association rather than direction, both LIN7A-to-partner and partner-to-LIN7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP catabolic process grouped by LIN7A-low versus LIN7A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN7A→partner) and Y-score (partner→LIN7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CMP catabolic process →	-0.187	-1.294	.009	.009	3	8
BREAST	Regulation of cell adhesion mediated by integrin →	-0.155	-1.954	<.001	<.001	3	7
LUNG_SCLC	ERBB2-EGFR signaling pathway →	-1.209	-2.538	<.001	<.001	3	7
LIVER	Alcohol biosynthetic process →	+0.094	+2.547	<.001	<.001	3	7
BONE	Homophilic cell-cell adhesion →	-0.118	-2.417	.004	<.001	3	7
LARGE_INTESTINE	Gamma-aminobutyric acid signaling pathway →	-0.244	-0.952	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,825 associations by consensus.

CMP catabolic process by LIN7A expression — BREAST

Explore this box plot interactively →