Across TCGA patient cohorts, LIN54 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,093 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIN54-associated proteins across cancer lineages are NCAPG, NCAPG_S674, and RFC2. Each is linked with LIN54 in more than 5 cancer types. Because this analysis shows association rather than direction, both LIN54-to-partner and partner-to-LIN54 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN54→partner) and Y-score (partner→LIN54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCAPG →	+0.540	+0.261	<.001	.002	3	6
UCEC	NCAPG_S674 →	+0.832	+0.473	<.001	<.001	3	6
HNSC	RFC2 →	+0.352	+0.326	<.001	.001	3	6
LSCC	ATAD2 →	+0.501	+0.399	<.001	<.001	3	6
HNSC	MCM3 →	+0.499	+0.365	<.001	<.001	3	6
PDAC	MCM4_T110 →	+1.402	+0.362	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,093 associations by consensus.

Exploration

LIN54 survival (RNA) · tumor vs normal (RNA) · all LIN54 data types