LIN54

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LIN54 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,597 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LIN54-associated GO terms across cancer lineages are Centriole replication, CMP biosynthetic process, and Centrosome duplication. Each is linked with LIN54 in more than 15 cancer types. Because this analysis shows association rather than direction, both LIN54-to-partner and partner-to-LIN54 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN54→partner) and Y-score (partner→LIN54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUECentriole replication →+0.144+0.929<.001<.001316
URINARY_TRACTCMP biosynthetic process →+0.155+0.796<.001<.001316
SOFT_TISSUECentrosome duplication →+0.132+0.947<.001<.001316
BREASTRegulation of chromosome condensation →+0.215+0.981<.001<.001316
SOFT_TISSUEPositive regulation of cell cycle →+0.095+0.674<.001<.001315
SOFT_TISSUERegulation of chromosome segregation →+0.148+0.792<.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,597 associations by consensus.

Exploration