LIN37

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LIN37 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,045 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible LIN37-associated GO terms across cancer lineages are Tubulin deacetylation, Maintenance of protein location in cell, and COPII-coated vesicle budding. Each is linked with LIN37 in more than 12 cancer types. Because this analysis shows association rather than direction, both LIN37-to-partner and partner-to-LIN37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tubulin deacetylation grouped by LIN37-low versus LIN37-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIN37→partner) and Y-score (partner→LIN37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHTubulin deacetylation →+0.110+0.676.002.004313
LIVERMaintenance of protein location in cell →+0.126+0.774<.001.004311
STOMACHCOPII-coated vesicle budding →+0.119+0.902<.001<.001311
SOFT_TISSUEMaintenance of protein localization in organelle →+0.101+0.470<.001.001311
LUNG_NSCLC_LUSCGolgi to plasma membrane protein transport →+0.145+0.713<.001.002310
LIVERMaintenance of protein location →+0.125+0.751<.001.005310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,045 associations by consensus.

Tubulin deacetylation by LIN37 expression — STOMACH

Box plot of Tubulin deacetylation in LIN37-low vs LIN37-high samples in STOMACH.

Explore this box plot interactively →

Exploration