Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, LIN28B mutation is significantly associated with the RNA expression of many other genes, with 4,238 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible LIN28B-associated genes across cancer lineages are IMMP1L, EIF3M, and YAF2. Each is linked with LIN28B in more than 1 cancer types. Because this analysis shows association rather than direction, both LIN28B-to-partner and partner-to-LIN28B results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (LIN28B→partner) and Y-score (partner→LIN28B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.