Across TCGA pan-cancer cohorts, LIN28AP2 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LIN28AP2 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LIN28AP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LIN28AP2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.
KIRC, KIRP, and LUSC are the cancer types where LIN28AP2 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.