LIMS3

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LIMS3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LIMS3’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LIMS3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LIMS3 is over-expressed in tumor.

THCA and KICH are the cancer types where LIMS3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LIMS3 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAAllAll+0.006.0242view →
KICHAllAll+0.022.0411view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LIMS3–THCA

Tumor-vs-normal expression box plot for LIMS3 RNA in THCA.

Open the THCA breakdown →

Exploration