LIMS1

Across TCGA patient cohorts, LIMS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,335 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIMS1-associated proteins across cancer lineages are ZYX, THNSL1, and TUBB6. Each is linked with LIMS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LIMS1-to-partner and partner-to-LIMS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMS1 versus ZYX in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMS1→partner) and Y-score (partner→LIMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZYX →	+0.423	+0.861	<.001	<.001	3	7
OV	THNSL1 →	-0.579	-0.844	<.001	<.001	3	7
LSCC	TUBB6 →	+0.459	+0.579	<.001	<.001	3	7
GBM	PDLIM4 →	+0.757	+0.554	<.001	<.001	3	7
BRCA	SERPINH1 →	+0.508	+0.483	<.001	<.001	3	7
OV	ITGA5 →	+0.523	+0.847	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,335 associations by consensus.

LIMS1 vs ZYX — OV

Explore this scatter interactively →