LIMK2

Across TCGA patient cohorts, LIMK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,432 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIMK2-associated proteins across cancer lineages are ITGAM, PGLYRP1, and AZU1. Each is linked with LIMK2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LIMK2-to-partner and partner-to-LIMK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMK2 versus ITGAM in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMK2→partner) and Y-score (partner→LIMK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGAM →	+0.519	+0.506	<.001	<.001	3	5
GBM	PGLYRP1 →	+0.843	+0.455	<.001	.002	3	5
GBM	AZU1 →	+0.846	+0.522	.001	.001	2	6
BRCA	PRTN3 →	+1.045	+0.530	<.001	<.001	3	4
CCRCC	PTGFRN →	+0.460	+0.382	<.001	.002	3	4
GBM	ZNF24 →	-0.302	-0.414	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,432 associations by consensus.

LIMK2 vs ITGAM — GBM

Explore this scatter interactively →