LIMK2

Across TCGA patient cohorts, LIMK2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,321 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIMK2-associated genes across cancer lineages are PPIAP4, FKTN, and RCOR3. Each is linked with LIMK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both LIMK2-to-partner and partner-to-LIMK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMK2 versus PPIAP4 in UCEC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMK2→partner) and Y-score (partner→LIMK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPIAP4 →	-0.478	-0.266	.009	.003	3	5
UCEC	FKTN →	-0.439	-0.265	.003	.004	2	5
LUAD	RCOR3 →	-0.385	-0.221	<.001	<.001	3	4
LSCC	NAA35 →	-0.341	-0.186	<.001	<.001	3	4
LSCC	STX17 →	-0.573	-0.284	<.001	<.001	3	4
LUAD	RMND5B →	-0.430	-0.207	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,321 associations by consensus.

LIMK2 vs PPIAP4 — UCEC

Explore this scatter interactively →