LIMK1

Across TCGA patient cohorts, LIMK1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,274 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIMK1-associated genes across cancer lineages are LILRB4, LILRB1, and TYROBP. Each is linked with LIMK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both LIMK1-to-partner and partner-to-LIMK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMK1 versus LILRB4 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMK1→partner) and Y-score (partner→LIMK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LILRB4 →	+1.073	+0.235	<.001	<.001	3	9
LUAD	LILRB1 →	+0.777	+0.342	<.001	<.001	3	8
HNSC	TYROBP →	+0.966	+0.246	<.001	<.001	3	8
OV	CXorf21 →	+1.137	+0.403	<.001	<.001	3	8
OV	CD180 →	+0.760	+0.287	.003	.004	3	8
OV	CCR5 →	+1.141	+0.332	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,274 associations by consensus.

LIMK1 vs LILRB4 — HNSC

Explore this scatter interactively →