Across TCGA patient cohorts, LIME1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,806 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIME1-associated proteins across cancer lineages are RBM12, CSE1L, and GMPPA. Each is linked with LIME1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LIME1-to-partner and partner-to-LIME1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIME1→partner) and Y-score (partner→LIME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM12 →	+0.296	+0.505	<.001	<.001	3	5
LSCC	CSE1L →	+0.423	+0.532	<.001	<.001	3	5
LSCC	GMPPA →	-0.340	-0.504	<.001	<.001	3	5
COAD	TAF4 →	+0.289	+0.706	<.001	<.001	3	5
GBM	PNN →	+0.416	+0.617	<.001	<.001	3	4
LSCC	TXNDC5 →	-0.523	-0.424	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,806 associations by consensus.

Exploration

LIME1 survival (RNA) · tumor vs normal (RNA) · all LIME1 data types