Across TCGA patient cohorts, LIME1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,755 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIME1-associated genes across cancer lineages are C16orf54, IGLV6-57, and ANKRD36BP2. Each is linked with LIME1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LIME1-to-partner and partner-to-LIME1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIME1→partner) and Y-score (partner→LIME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C16orf54 →	+1.673	+1.473	<.001	<.001	3	6
UCEC	IGLV6-57 →	+4.230	+1.337	<.001	<.001	3	6
UCEC	ANKRD36BP2 →	+1.907	+1.266	<.001	<.001	3	6
CCRCC	LINC02384 →	+1.166	+0.699	.001	<.001	3	6
UCEC	SLA2 →	+1.598	+1.304	<.001	<.001	3	5
UCEC	PIM2 →	+1.996	+1.521	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,755 associations by consensus.

Exploration

LIME1 survival (RNA) · tumor vs normal (RNA) · all LIME1 data types