LIME1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LIME1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,528 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LIME1-associated GO terms across cancer lineages are mRNA splice site recognition, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Viral transcription. Each is linked with LIME1 in more than 13 cancer types. Because this analysis shows association rather than direction, both LIME1-to-partner and partner-to-LIME1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIME1→partner) and Y-score (partner→LIME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTmRNA splice site recognition →+0.143+1.253<.001<.001314
BONEPositive regulation of transcription of nucleolar large rRNA by RNA polymerase I →+0.168+1.462<.001<.001314
UPPER_AERODIGESTIVE_TRACTViral transcription →+0.159+1.511<.001<.001314
UPPER_AERODIGESTIVE_TRACTCilium-dependent cell motility →-0.104-1.200<.001<.001313
BONEPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.192+1.457<.001<.001313
LUNG_SCLCPromoter clearance during DNA-templated transcription →+0.143+1.139<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

Exploration