LIMD2

Across TCGA cell cohorts, LIMD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,105 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LIMD2-associated GO terms across cancer lineages are DNA-templated transcription initiation, Protein-DNA complex organization, and Transcription initiation at RNA polymerase II promoter. Each is linked with LIMD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both LIMD2-to-partner and partner-to-LIMD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by LIMD2-low versus LIMD2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMD2→partner) and Y-score (partner→LIMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.082	+2.326	.005	.003	3	12
BONE	Protein-DNA complex organization →	+0.066	+2.241	<.001	<.001	3	12
BONE	Transcription initiation at RNA polymerase II promoter →	+0.067	+2.446	.001	<.001	3	11
BONE	Protein-DNA complex assembly →	+0.102	+3.045	<.001	<.001	3	11
STOMACH	AMPA glutamate receptor clustering →	+1.181	+2.210	.001	.002	3	10
STOMACH	Glutamate receptor clustering →	+1.181	+2.210	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,105 associations by consensus.

DNA-templated transcription initiation by LIMD2 expression — BONE

Explore this box plot interactively →