LIMD1

Across TCGA patient cohorts, LIMD1 mutation is significantly associated with the RNA expression of many other genes, with 1,606 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LIMD1-associated genes across cancer lineages are VSIG4, FCER1G, and RN7SL62P. Each is linked with LIMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIMD1-to-partner and partner-to-LIMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VSIG4 grouped by LIMD1-low versus LIMD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMD1→partner) and Y-score (partner→LIMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VSIG4 →	+0.929	+2.415	<.001	.003	3	2
UCEC	FCER1G →	+0.653	+1.925	.006	.005	3	2
SKCM	RN7SL62P →	+0.198	+4.508	<.001	.001	3	2
COAD	SLC25A39P2 →	+0.179	+5.557	<.001	.001	3	2
UCEC	CYB5B →	+0.526	+2.828	<.001	<.001	3	2
UCEC	FCGR3A →	+1.049	+1.925	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,606 associations by consensus.

VSIG4 by LIMD1 expression — UCEC

Explore this box plot interactively →