LIMD1

Across TCGA cell cohorts, LIMD1 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LIMD1-associated genes across cancer lineages are LGALS13, TEX55, and IL3. Each is linked with LIMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIMD1-to-partner and partner-to-LIMD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS13 grouped by LIMD1-low versus LIMD1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMD1→partner) and Y-score (partner→LIMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	LGALS13 →	+0.081	+4.981	.008	.008	3	1
CNS	TEX55 →	+0.049	+5.321	<.001	.005	3	1
CNS	IL3 →	+0.038	+4.981	<.001	.008	3	1
CNS	OR11H6 →	+0.021	+5.321	<.001	.005	3	1
CNS	FGF3 →	+0.040	+4.981	.001	.008	3	1
LARGE_INTESTINE	DESI1 →	+0.452	+3.451	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

LGALS13 by LIMD1 expression — CNS

Explore this box plot interactively →