LIMA1

Across TCGA patient cohorts, LIMA1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,863 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LIMA1-associated genes across cancer lineages are CREB3L1, SMAGP, and FHL2. Each is linked with LIMA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LIMA1-to-partner and partner-to-LIMA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMA1 versus CREB3L1 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMA1→partner) and Y-score (partner→LIMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CREB3L1 →	+1.585	+0.566	<.001	<.001	3	6
UCEC	SMAGP →	+1.043	+0.381	<.001	<.001	3	6
COAD	FHL2 →	+0.710	+0.444	<.001	<.001	3	5
GBM	TAOK3 →	+0.611	+0.423	<.001	.001	3	5
BRCA	SLC40A1 →	+1.696	+0.546	<.001	<.001	3	5
BRCA	CBX2 →	-1.717	-0.553	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,863 associations by consensus.

LIMA1 vs CREB3L1 — BRCA

Explore this scatter interactively →