LIMA1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LIMA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,087 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LIMA1-associated GO terms across cancer lineages are Intestinal lipid absorption, Lipid digestion, and Intestinal cholesterol absorption. Each is linked with LIMA1 in more than 14 cancer types. Because this analysis shows association rather than direction, both LIMA1-to-partner and partner-to-LIMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intestinal lipid absorption grouped by LIMA1-low versus LIMA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMA1→partner) and Y-score (partner→LIMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYIntestinal lipid absorption →+0.304+1.466<.001<.001315
LUNG_SCLCLipid digestion →+0.618+1.306.007.004315
LUNG_SCLCIntestinal cholesterol absorption →+0.636+1.552.005<.001314
LARGE_INTESTINENegative regulation of actin filament depolymerization →+0.174+1.118<.001<.001314
OESOPHAGUSRegulation of actin filament organization →+0.068+1.871<.001.001314
BONERegulation of actin filament depolymerization →+0.170+1.877<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,087 associations by consensus.

Intestinal lipid absorption by LIMA1 expression — OVARY

Box plot of Intestinal lipid absorption in LIMA1-low vs LIMA1-high samples in OVARY.

Explore this box plot interactively →

Exploration