LILRP2

Across TCGA patient cohorts, LILRP2 mutation is significantly associated with the RNA expression of many other genes, with 1,512 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LILRP2-associated genes across cancer lineages are SERAC1, ZWINT, and SHLD3. Each is linked with LILRP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LILRP2-to-partner and partner-to-LILRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERAC1 grouped by LILRP2-low versus LILRP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LILRP2→partner) and Y-score (partner→LILRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SERAC1 →	+0.433	+3.051	<.001	<.001	3	3
UCEC	ZWINT →	+0.820	+2.540	.003	.009	3	3
SKCM	SHLD3 →	+0.430	+1.328	.001	.008	3	3
UCEC	ZCCHC4 →	+0.507	+3.600	<.001	.001	3	3
HNSC	EIF3JP1 →	+0.215	+3.654	<.001	.009	3	3
UCEC	CYB5RL →	+0.517	+3.370	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,512 associations by consensus.

SERAC1 by LILRP2 expression — SKCM

Explore this box plot interactively →